Revisiting intrapleural fibrinolysis in empyema
نویسندگان
چکیده
منابع مشابه
Intrapleural fibrinolytics in management of empyema thoracis.
STUDY OBJECTIVE To determine the success and complication rates of fibrinolytic therapy (FL) in the treatment of thoracic empyema. DESIGN AND PATIENTS Between December 1992 and November 1994, all patients referred with empyema thoracis (ET) were offered FL. FL consisted of streptokinase (275,000 +/- 170,000 IU) or urokinase (121,000 +/- 57,000 IU) daily for a mean of 6.2 +/- 2.1 days. SETTI...
متن کاملIntrapleural streptokinase in the management of empyema.
BACKGROUND Significant morbidity and mortality result from the ineffective evacuation of empyema. Failure of conventional first line treatment with closed intercostal tube drainage and antibiotic therapy may result in fibrin deposition and loculated empyema. Enzymatic debridement using intrapleural instillation of streptokinase is a non-invasive therapeutic option which may obviate the need for...
متن کاملIntrapleural therapy in management of complicated parapneumonic effusions and empyema
Empyema thoracis causes high mortality, and its incidence is increasing in both children and adults. Parapneumonic effusions (PPEs) develop in about one-half of patients hospitalized with pneumonia, and their presence increases mortality by about four-fold. PPEs can be divided into simple PPEs, complicated PPEs, and frank empyema. Two guideline statements on the management of PPEs in adults hav...
متن کاملIntrapleural Streptokinase in the Management of Pleural Empyema
thoracic surgery with poor prognosis unless treated properly. It can cause sepsis and other complications which may increase morbidity and mortality. The treatment of choices in pleural empyema are thoracentesis, intercostal tube or pleural catheter drainage, video-assisted thoracic surgery (VATS) and open surgery (1, 2). Tube drainage often fails if the empyema is loculated with fibrinous adhe...
متن کاملIntrapleural administration of DNase alone for pleural empyema.
INTRODUCTION Pleural empyema is a severe complication of various diseases. The essential is the inserting a drain into the pleural cavity and evacuation of the pus. Sometimes the pus is very thick and its evacuation and re-expansion of the lung is very difficult. METHODS We report a group of 10 patients with intrapleural administration of Pulmozyme (dornase alpha) in dosages of either 2.5 mg ...
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ژورنال
عنوان ژورنال: Thorax
سال: 2011
ISSN: 0040-6376,1468-3296
DOI: 10.1136/thoraxjnl-2011-201045